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NUCLEIC ACID PROBES AND BROAD-RANGE PRIMERS FROM REGIONS IN TOPOISOMERASE GENES, AND METHODS IN WHICH THEY ARE USED
NUCLEIC ACID PROBES AND BROAD-RANGE PRIMERS FROM REGIONS IN TOPOISOMERASE GENES, AND METHODS IN WHICH THEY ARE USED
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机译:拓扑异构酶基因区域中的核酸探针和广谱起点及其使用方法
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摘要
The invention relates to nucleic acid probes and to broad-range primers that are useful in the identification of bacterial species and the diagnosis of bacterial infections. Especially, the invention relates to specific nucleic acid probes that originate from hyper-variable regions situated near the conserved sequences of topoisomerase genes of infection-causing bacteria. The invention also relates to broad-range primers originating from the conserved regions of topoisomerase genes. In addition, the invention relates to the use of these nucleic acid probes and broad-range primers in the diagnosis of bacterial infections as well as to diagnostic methods in which these nucleic acid probes and broad-range primers are used.
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