COMPOUNDS FOR THE PHOTODCONTAMINATION OF PATHOGENS IN THE BLOOD.

摘要

SORALENE COMPOUNDS THAT HAVE SUBSTITUTIONS ON THE 4,4 '', 5 '' AND 8 POSITIONS OF THE SORALENE, WHICH ALLOW ENHANCED LINKS TO THE NUCLEIC ACID OF PATHOGEN, ARE SYNTHETIZED. THE SUPERIOR SORALENE LINK LEVELS OR THE LOWER MUTAGENICITY ARE DESCRIBED, RESULTING IN A RELIABLE AND MORE EFFICIENT INACTIVATION OF SAFE PATHOGEN MODE IN BLOOD PRODUCTS. THE INVENTION INCLUDES THE INACTIVATION METHODS USING THE NEW SURVEYS THAT DO NOT COMMIT THE FUNCTION OF BLOOD PRODUCTS FOR TRANSFUSION.