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AUTONOMOUSLY REPLICATING KSHV CIS-ACTING ELEMENTS
AUTONOMOUSLY REPLICATING KSHV CIS-ACTING ELEMENTS
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机译:自主替换KSHV CIS-ACTING元素
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摘要
This invention provides methods of reducing a replication of a gammaherpesvirus genome, treating a KSHV infection, and treating or reducing an incidence of a KSHV-associated disease, comprising contacting a subject with a composition that inhibits initiation of DNA replication from a region of a genome of a gammaherpesvirus. The invention also provides isolated DNA molecules capable of episomal replication in a eukaryotic cell, and methods of delivering a recombinant protein or therapeutic RNA molecule, comprising same.
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