SMALL INTERFERING RNA SPECIFIC FOR COXSACKIEVIRUS B RNA AND THERAPEUTIC AGENT COMPRISING THE SAME

摘要

The present invention relates to a therapeutic agent comprising a coxsackie virus B (Coxsackievirus B) specific small interfering RNA, and the active ingredient in this RNA. More specifically, and interfering RNA (siRNA) of the invention include the capsid protein, and at least the sequence of possible inhibition of RNA specifically the nonstructural protein portion of the coxsackie virus, according to the coxsackie virus in vitro and in vivo cell degeneration and reduce the effects, cocks can be very effectively used for the prevention and treatment of Kawasaki disease viral genome replication and proliferation of objects caused by coxsackie virus infection hayeoteumeuro inhibition. ; Coxsackievirus B (Coxsackievirus B), RNA interference (RNA interference), myocarditis (Myocardities), dilated cardiomyopathy (Dilated Cardiomyopathy).