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Small interfering RNA specific for neurotensin mRNA and Therapeutic agent for tumor comprising the same
Small interfering RNA specific for neurotensin mRNA and Therapeutic agent for tumor comprising the same
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机译:对神经降压素mRNA有特异性的小干扰RNA和包含该小干扰RNA的肿瘤治疗剂
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摘要
A tumor drug including siRNA which is specific for Neurotensin mRNA is provided to increase susceptibility of a tumor cell about gamma radiation and cisplatin anti-cancer drug by suppressing expression of a gene of Neurotensin. A composition for treating cancer includes a carrier combined to mRNA of a gene of Neurotensin having a sequence number 3 pharmaceutically. siRNA includes an antisense sequence combining with a sense sequence and the sense sequence having 17-29 of basic length selected from base sequence of mRNA. Tumor is gastric cancer, lung cancer, prostate cancer, pancreatic cancer, and colorectal cancer.
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