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The agent having anti-diacyl glycerol acyl transferase activity and the pharmaceutical composition for preventing and treating hyperlipidemia and obesity comprising the same
The agent having anti-diacyl glycerol acyl transferase activity and the pharmaceutical composition for preventing and treating hyperlipidemia and obesity comprising the same
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机译:具有抗二酰基甘油酰基转移酶活性的药物和用于预防和治疗高脂血症和肥胖症的药物组合物
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摘要
The present invention includes a thiol Dick E DGAT ( diacylglycerol acyltransferase , Diacyl glycerol acyl transferase ) relates to a pharmaceutical composition for preventing and treating hyperlipidemia and obesity comprising active agents and which , comprises a thiol Dick E as an active ingredient , DGAT inhibitors and prevention of hyperlipidemia and obesity , which represents them as an active ingredient, a DGAT inhibitory activity and the pharmaceutical composition is provided for treatment . ; Dick useful DGAT activity inhibitor comprising a thiol E according to the present invention is excellent in activity as compared to conventional DGAT inhibitor for the treatment and prevention of obesity and hyperlipidemia it can be used .
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机译:本发明涉及一种硫醇Dick E DGAT(二酰基甘油酰基转移酶),涉及一种预防和治疗高脂血症和肥胖症的包含活性剂的药物组合物,其包含硫醇Dick E作为有效成分,DGAT抑制剂和预防。代表它们作为有效成分的高脂血症和肥胖症,具有DGAT抑制活性,并且提供了用于治疗的药物组合物。 ;与用于治疗和预防肥胖症和高脂血症的常规DGAT抑制剂相比,根据本发明的包含硫醇E的Dick有用的DGAT活性抑制剂具有优异的活性。
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