PREPARATION METHOD OF BIODEGRADABLE POROUS POLYMER SCAFFOLDS FOR TISSUE ENGINEERING USING HYDROGEN PEROXIDE

摘要

A method for preparing a biodegradable porous polymer scaffold is provided to produce a biodegradable porous polymer scaffold for tissue engineering, which has no phenomena for pore clogging and harmful substances excretion and remain, and has an open structure with higher surface area and porosity. A method for preparing a biodegradable porous polymer scaffold for tissue engineering comprises the steps of: (a) adding a hydrogen peroxide-containing compound to a polymer solution which is obtained by dissolving a biodegradable polymer into a solvent, and mixing the resulting solution homogeneously; (b) allowing the solution obtained in the step (a) to stand at a temperature of -196 deg.C to a normal temperature so as to evaporate the solvent; and (c) introducing the polymer specimen obtained in the step (b) into an aqueous solution containing a catalyst for decomposition of hydrogen peroxide and foaming the resultant, followed by drying.