首页> 外国专利> BIODEGRADABLE POROUS POLYMER SCAFFOLDS BY USING EFFERVESCENT MIXTURE FOR TISSUE ENGINEERING AND THEIR PREPARATION METHODS

BIODEGRADABLE POROUS POLYMER SCAFFOLDS BY USING EFFERVESCENT MIXTURE FOR TISSUE ENGINEERING AND THEIR PREPARATION METHODS

机译:利用泡腾混合物进行组织工程可生物降解的多孔聚合物脚手架及其制备方法

摘要

The present invention relates to a method for preparing a biodegradable porous polymer support for tissue engineering, wherein the method is used to prepare a polymer specimen using a polymer solution containing a biodegradable polymer and an effervescent mixture, followed by boiling under a boiling medium such as an alcohol mixed solution. (Foaming) and drying.;The present invention also relates to a biodegradable porous polymer support for tissue engineering prepared by the above method, wherein the biodegradable porous polymer support is easy to control pore size, has high porosity, and is continuously connected to a bubble structure (open space). cell structure).;The biodegradable porous polymer support according to the present invention and a method for producing the support are generated by a salt leaching technique and a gas foaming technique which have been generally applied in the manufacture of a conventional polymer scaffold. It is an alternative to solve the porous clogging of the surface, the complex manufacturing process and the secretion and remaining of harmful substances, and has the advantage of being able to regenerate almost all tissues and organs by tissue engineering.
机译:本发明涉及一种用于组织工程的可生物降解的多孔聚合物载体的制备方法,其中该方法用于通过使用包含可生物降解的聚合物和泡腾混合物的聚合物溶液来制备聚合物样品,然后在诸如酒精混合溶液。 (发泡)和干燥。本发明还涉及通过上述方法制备的用于组织工程的可生物降解的多孔聚合物载体,其中该可生物降解的多孔聚合物载体易于控制孔径,具有高孔隙率并且连续地连接至气泡结构(开放空间)。本发明的可生物降解的多孔聚合物载体和制备该载体的方法是通过盐浸技术和气体发泡技术产生的,所述盐浸技术和气体发泡技术通常用于常规聚合物支架的制造中。它是解决表面多孔堵塞,制造过程复杂以及有害物质分泌和残留的一种替代方法,并且具有能够通过组织工程再生几乎所有组织和器官的优势。

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