METHOD FOR RADIONUCLIDE MARKING INTESTINE BACILLUS MICROORGANISM FOR SCINTIGRAPHIC INVESTIGATION

摘要

FIELD: biotechnology, medicine, microbiology.;SUBSTANCE: method involves labeling intestine bacillus microorganisms with radionuclide by incubation of E. coli culture in solution of the reagent "Pirfoteks, ^99mTc", culturing microorganisms with ^99mTc-technetate and the following purification of labeled bacterial cells by centrifugation. Using the invention provides preparing the viable culture of intestine bacillus with high specific radioactivity and no containing free ^99mTc-pertechnetate in extracellular medium.;EFFECT: improved method for marking microorganisms.;3 tbl, 7 dwg, 2 ex