METHOD FOR PREPARING 1-3-HYDROXY-3-(PYRID-4-YLPROP-1-YL-1,2-DIHYDRO60FULLERENES

摘要

FIELD: organic chemistry, chemical technology.;SUBSTANCE: invention relates to a method for synthesis of 1-[3-hydroxy-3-(pyrid-4-yl)prop-1-yl]-1,2-dihydro[60]fullerene. Method involves interaction of C₆₀ with triethylaluminum in the presence of catalyst, in argon atmosphere, at room temperature and under atmosphere pressure, in toluene medium for 8 h followed by addition of nickel-containing catalyst and 4-pyridinecarbaldehyde at temperature -15°C followed by stirring the reaction mass at room temperature for 6-10 h and the following hydrolysis. The total yield of end substances after hydrolysis of the reaction mass is 48-69%. Proposed compounds can be used in fine organic synthesis, in manufacture of drugs and biologically active substances. Invention provides the development of method for synthesis of novel fullerene-containing alcohols.;EFFECT: improved method of synthesis.;1 tbl, 1 ex