ASIA-1-TYPE FOOT-AND-MOUTH DISEASE VIRUS STRAIN FOR PRODUCING OF DIAGNOSTIC AND/OR VACCINE PREPARATIONS

摘要

FIELD: biotechnology, virology.;SUBSTANCE: claimed strain is obtained by passaging of epizootic isolate on sensitive hetero- and homologous cell cultures. Virus strain is reproduced in sensitive cell cultures and after incubation for 18-24 h 6.0-7.66 lg TCD₅₀/ml is accumulated. In case of mass infection strain takes cytopathic effect over 5 hours, and retains starting characteristics for 10 passages.;EFFECT: strain of high biological, antigenic and immunogenic activity.;1 dwg, 7 tbl, 5 ex