METHODS FOR SYNTHESIS OF APLIDINE AND NOVEL ANTI-TUMOR DERIVATIVES, METHODS FOR THEIR INDUSTRIAL PREPARING AND USING

摘要

FIELD: organic chemistry, antibiotics, medicine, oncology.;SUBSTANCE: invention relates to novel derivatives of aplidine possessing anti-tumor activity and represented by the general formula: ;EFFECT: valuable medicinal property of compound, improved methods of synthesis and preparing.;28 cl, 3 tbl, 121 ex