Use of amphiregulin as a protective agent in acute liver injury

摘要

The invention relates to the use of amphiregulin in the production of a medicament which can be used to treat acute hepatic injury and which is administered, for example, in order to: promote a primary endogenous protective reaction in the hepatic tissue against acute hepatic injury, promote DNA synthesis in hepatocytes, prevent the death of hepatocytes in the hepatic tissue of patients with acute hepatic injury, stimulate the regeneration of the remaining hepatic parenchyma following an acute hepatic injury of any aetiology, and stimulate hepatic regeneration following a partial hepatectomy. According to the invention, the amphiregulin is administered as a hepatoprotector medicine for patients with acute hepatic injury of any aetiology and/or as a hepatoprotector medicine and stimulant of hepatocytic regeneration for recipients of a liver transplant from a living donor or a cadaver donor.