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detection method of toxins that ion-binding polymer containing substrate, the detection sensor and pathogens or pathogen containing the substrate to produce

机译:含有离子结合聚合物的底物的毒素检测方法,检测传感器和含有底物的病原体或病原体产生

摘要

An objective of the present invention is to provide ionic polymers that can provide for polymer-comprising substrates whose surfaces can stably and easily immobilize ligands such as sugar chains interacting with biological substances, in which the ligand portion exists stably even in water or buffer, and its detection capability does not decrease for a long period of time; and substrates comprising the polymers. The ionic polymer of this invention comprises two or more ionic functional groups (A) and two or more biointeracting groups represented by formula L-X-B-[wherein, L denotes a ligand capable of interacting with a biological substance, X denotes a spacer, and B denotes a binding group] as side chains covalently bound to a main chain polymer.
机译:本发明的目的是提供离子聚合物,其可提供含聚合物的底物,其表面可稳定且容易地固定配体例如糖链与生物物质相互作用,其中配体部分即使在水或缓冲液中也稳定存在,并且其检测能力不会长期降低;以及包含所述聚合物的基材。本发明的离子聚合物包含两个或多个离子官能团(A)和两个或多个由式LXB-表示的生物相互作用基团[其中,L表示能够与生物物质相互作用的配体,X表示间隔基,B表示[结合基团]作为与主链聚合物共价结合的侧链。

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