compound, use thereof, pharmaceutical composition, method for inhibiting hepatitis c virus polymerase and / or treating or preventing a disease due to hepatitis c virus, and, process for preparing a compound

摘要

COMPOUND, USE OF THE SAME, PHARMACEUTICAL COMPOSITION, METHOD FOR INHIBITING HEPATITE C VIRUS POLYMERASE AND / OR TREATING OR PREVENTING A DISEASE DUE TO HEPATITIS C AND VIRUS, PROCESS FOR PREPARING A COMPOUND. The present invention relates to the tetracyclic indole compounds of formula (1); wherein R˜, R�, A, Ar, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of hepatitis virus infection. Ç.