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Derivatives of pyrimidine Compounds, inhibitors of prostaglandin D2; Pharmaceutical Composition and use for treating allergic or inflammatory disorders such as allergic rhinitis, Asthma and COPD.

机译:嘧啶化合物的衍生物,前列腺素D2的抑制剂;药物组合物和用于治疗过敏性或炎性疾病例如过敏性鼻炎,哮喘和COPD的药物。

摘要

This invention is directed to a compound of formula (I): wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).
机译:本发明涉及式(I)的化合物:其中R1,R2,R3,R4和L1如本文所定义,包含该化合物的药物组合物,以及该化合物在治疗变应性和/或炎性疾病中的用途,特别是变态反应性鼻炎,哮喘和/或慢性阻塞性肺疾病(COPD)等疾病。

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