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ANTAGONISTS OF THE IGE RECEPTOR

机译:IGE受体的拮抗剂

摘要

The invention provides novel compounds which bind to the high affinity receptor for immunoglobulin E (IgE) designated FcepsilonRI and methods for identifying and preparing such compounds. In particular aspects, the invention provides to the treatment of disorders mediated by IgE utilizing the novel compounds of the invention. The invention also provides composition, such as pharmaceutical compositions, comprising the novel compounds, as well as for their use in research, diagnostic, therapeutic, and prophylactic methods.
机译:本发明提供了与命名为FcepsilonRI的免疫球蛋白E(IgE)的高亲和力受体结合的新型化合物,以及鉴定和制备此类化合物的方法。在特定方面,本发明提供利用本发明的新化合物治疗由IgE介导的疾病。本发明还提供了包含新化合物的组合物,例如药物组合物,以及它们在研究,诊断,治疗和预防方法中的用途。

著录项

  • 公开/公告号AT402958T

    专利类型

  • 公开/公告日2008-08-15

    原文格式PDF

  • 申请/专利权人 GENENTECH INC.;

    申请/专利号AT20010983090T

  • 申请日2001-09-26

  • 分类号C07K14/705;G01N33/50;A61K38;A61K38/17;A61P1/04;A61P1/12;A61P1/16;A61P1/18;A61P3/10;A61P5/14;A61P7/02;A61P7/06;A61P9/10;A61P11;A61P13/02;A61P13/12;A61P15/08;A61P17;A61P17/02;A61P17/06;A61P19/02;A61P25/28;A61P29;A61P31/04;A61P31/12;A61P37/02;A61P37/08;A61P43;C07K1;C07K7/06;C07K7/08;C07K14;C07K16;G01N33/15;G01N33/566;G01N33/68;

  • 国家 AT

  • 入库时间 2022-08-21 20:04:50

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