2-AMINOBENZOTIAZOLES AS INVESTED AGONISTS OF THE CB1 RECEIVER.

摘要

Compounds of formula (I) (See formula) R 1 is phenyl or phenyl mono-, di- or tri-substituted, independently of one another by halogen, alkoxy of 1 to 8 carbon atoms, alkyl of 1 to 8 carbon atoms, alkoxy from 1 to 8 halogenated carbon atoms or dialkylamino from 1 to 8 carbon atoms; R2 is phenyl or phenyl mono-di- or tri-substituted independently of one another by halogen, alkyl of 1 to 8 halogenated carbon atoms, nitro or cyano; R3 is hydrogen, alkyl of 1 to 8 carbon atoms, benzyl, alkoxy of 1 to 8 carbon atoms, halogen, cyano, nitro, amino, -NHSO2-R3a or -NHCO-R3b; R3a is alkyl of 1 to 8 carbon atoms, dialkylamino of 1 to 8 carbon atoms, benzyl, phenyl or phenyl mono-, di- or tri-substituted, independently of each other by alkyl of 1 to 8 carbon atoms; R3b is benzyl, phenyl or mono-, di-, tri- substituted phenyl, independently from each other by alkyl of 1 to 8 carbon atoms; or a pharmaceutically acceptable salt thereof, for use as a therapeutically active substance.