METHODS OF REDUCING VISCERAL FAT BY INCREASING LEVELS OF INSULIN-LIKE GROWTH FACTOR-I (IGF-I)

摘要

The present invention provides methods and compositions for reducing visceral fat by administering to the subject a therapeutically effective amount of a compound that increases the bioactive serum levels of insulin-like growth factor-I (IGF-I) in the subject, thereby ameliorating negative effects of visceral obesity. The invention is useful in the treatment, prevention, or amelioration of one or more symptoms of visceral obesity or IGF-I deficiency related condition, including, for example, cardiovascular disease and the metabolic syndrome.