SYTEM FOR OPTIMIZING TREATMENT STRATEGIES USING A PATIENT-SPECIFIC RATING SYSTEM

摘要

The combined effects of a selected treatment option on multiple causes of morbidity or mortality are simulated for evaluation. Various patient-specific (620) and model-specific (610) parameters, including parameters related to the diseases to be modeled, are used in modeling (630) the incidence and mortality rates for each disease. These disease-specific models are used for defining a set of health states (640) having initial probabilities, which are used to formulate a transition matrix (650) used in matrix calculation to obtain output matrix Q (655). If additional cycles are needed (660), the transition matrix is updated (650) and matrix calculation is performed (655) using the updated transition matrix. Otherwise, the final output matrix Q (655) is utilized for calculation of values (670) needed for determining an overall treatment score. The calculated values (670) and/or values from Q (655) are combined (680) with patient or numeric scores from other treatment choice-related domains (675) to obtain a raw score that is used to produce a patient-specific score (690) for a selected treatment option.