首页> 外国专利> PSEUDOCERAMIDES AND PHARMACEUTICAL AND/OR COSMETIC COMPOSITIONS DESIGNED FOR ADMINISTRATION TO THE SKIN CONTAINING THE SAME

PSEUDOCERAMIDES AND PHARMACEUTICAL AND/OR COSMETIC COMPOSITIONS DESIGNED FOR ADMINISTRATION TO THE SKIN CONTAINING THE SAME

机译:伪神经酰胺和药用和/或化妆品成分,旨在管理含有相同成分的皮肤

摘要

Pharmaceutical and/or cosmetic compositions designed for application to the human or animal skin, comprising a pseudoceramide of general formula (I), wherein RSUP1/SUP is an alkyl with the chain length of from CSUB12/SUB to CSUB20/SUB; RSUP2/SUP is an alkyl or alkenyl with the chain length of from CSUB15/SUB to CSUB29/SUB, the minimal number of carbons in the molecule being 36, in amounts of from 0.01 to 20 weight %, based on the total weight of the composition, in a pharmaceutically acceptable vehicle. The compositions are designed for relipidization of the skin as well as for supplementary treatment of skin diseases associated with lowered lipid content and increased skin permeability. They can be used for treatment of damaged, dry or ageing skin and skin adnexa or for prevention of skin damage and skin adnexa. Novel pseudoceramides of general formula (II) are also described.
机译:设计用于人或动物皮肤的药物和/或化妆品组合物,包含通式(I)的假神经酰胺,其中R 1 是链长为C 12的烷基到C 20 ; R 2 是链长为C 15 至C 29 的烷基或烯基,分子中的最小碳数为36含量为组合物总重量的0.01至20%(重量),在药用载体中。该组合物被设计用于皮肤的脂化以及用于与降低的脂质含量和增加的皮肤渗透性有关的皮肤疾病的补充治疗。它们可用于治疗受损,干燥或老化的皮肤和皮肤附件,或用于预防皮肤损伤和皮肤附件。还描述了通式(II)的新型假神经酰胺。

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