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MEDICINAL COMPOSITION FOR INHIBITING PROPAGATION OF HUMAN IMMUNODEFICIENCY VIRUS

机译:抑制人体免疫缺陷病毒传播的药物组合物

摘要

The invention relates to medicinal compositions based on glycyrrhizic acid which makes it possible to increase the bioaccessibility of compositions and is used in medicine, virology and pharmacology, for example, in the form of an inhibitor used against the propagation of a human immunodeficiency virus. Said invention increases the bioaccessibility of a biologically active component embodied in the form of a glycyrrhizic acid derivative, for example di- and tri-nicotinate of glycyrrhizic acid. The inventive medicinal composition used for inhibiting propagation of a human immunodeficiency virus comprises sodium carbonate and glycyrrhizic acid derivatives in the form of di- and tri-nicotinate of glycyrrhizic acid of general formula I, wherein R is II or H, in which two and /or three of said R are II. The mass ratio of di- and/or tri-nikotinate of glycyrrhizic acid and sodium carbonate in a composition ranges from 3:1 to 1:3.
机译:本发明涉及基于甘草酸的药物组合物,其可以增加组合物的生物利用度,并且以例如用于抵抗人免疫缺陷病毒繁殖的抑制剂的形式用于医学,病毒学和药理学。所述发明增加了以甘草次酸衍生物例如甘草次酸的二烟酸酯和三烟酸酯形式体现的生物活性成分的生物利用度。用于抑制人免疫缺陷病毒繁殖的本发明药物组合物包含碳酸钠和甘草酸衍生物,其形式为通式I的甘草酸的二烟酸酯和三烟酸酯,其中R为II或H,其中两个和/或所述R中的三个为II。组合物中甘草次酸的二和/或三烟酸酯和碳酸钠的质量比为3:1至1:3。

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