ADENOVIRUS-BASED GENETIC VACCINES FOR BIODEFENSE

摘要

Embodiments of the present invention include the construction and generation of a multi-use adenoviral vaccine platform applicable to biodefense, and emerging and re- emerging infectious diseases. Adenoviral vaccines of the invention will elicit an immune response against pathogenic organisms that cause such infectious diseases. In certain aspects of the invention, the pathogenic organisms include, but are not limited to EEEV and Y. pestis. Further embodiments of the invention include compositions and methods related to such adenoviral vaccines.