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DISRUPTED ADENOVIRUS-BASED VACCINE AGAINST DRUGS OF ABUSE
DISRUPTED ADENOVIRUS-BASED VACCINE AGAINST DRUGS OF ABUSE
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机译:扰乱基于腺病毒的疫苗免受滥用药物
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摘要
The invention is directed to an adenovirus-antigen conjugate comprising (a) a disrupted adenovirus with a coat protein and (b) an antigen conjugated to the coat protein of the disrupted adenovirus, as well as a conjugate comprising (a) a disrupted adenovirus with a coat protein and (b) an antigen conjugated to the coat protein of the disrupted adenovirus. The invention also provides a method of inducing an immune response against an antigen in a human using the aforementioned conjugates. The invention further provides an adeno-associated viral vector comprising a nucleic acid sequence which encodes an antibody directed against cocaine.
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