METHOD AND KIT FOR DETERMINING CHIMERISM AFTER STEM CELL TRANSPLANTATION USING MITOCHONDRIAL DNA MICROSATELLITES AS MARKERS

摘要

Disclosed are a method and a kit for qualitatively and quantitatively determining chimerism after stem cell transplantation using mitochondrial DNA (mtDNA) hypervariable (HV) region, nucleotide position 303 poly C and/or 16184 poly C, as a marker (s). The method is easy and simple, and has extremely high sensitivity and specificity as compared to ones using nuclear DNA markers for determining chimerism after stem cell transplantation.