RECOMBINANT MAMMALIAN CELL FOR SCREENING A SUBSTANCE PREVENTING AND TREATING AIDS AND SCREENING METHOD USING THE SAME

摘要

For screen the substance of recombinant mammalian cells AIDS prevention of the present invention and treatment and unlatching sum be more specifically for expression (expression cassette) and HIV ψ () sequence and a reporter HIV NC protein expression boxes HIV NC protein recombinant mammalian cells and a screening method is used identical transformation reporter gene expression box (expression cassette) expression in it as a screening method. Recombinant mammalian cells and screening method it is of the invention have the effect of providing a kind of system, may search for for a kind of substance, inhibit the interaction of HIV NC protein and HIV psi sequences using eukaryotic cells. Therefore, the present invention may search for a kind of substance, HIV NC protein and HIV psi sequences with each new substance, inhibit action, its new means and AIDS prevention that search is provided and being related to effectively provide a kind of novel screen method that HIV encapsulation treatment.