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Results of a Micronucleus Screening Test In Vivo Performed on the Basis of OECD 474 Mammalian Erythrocyte Micronucleus Test with Test Substance LS 5869752.

机译：基于经测试物质Ls 5869752的OECD 474哺乳动物红细胞微核试验在体内进行的微核筛选试验的结果。

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年度 2012
页码 1-2
总页数 2
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Toxicology; Health effects; Micronucleus screening test; Chronic toxicity; Acute toxicity;

机译：毒理学;健康影响;微核筛选试验;慢性毒性;急性毒性;

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1. Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test. [J] . Cariou O, Laroche Prigent N, Ledieu S, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2010,第2期

机译：在赛诺菲安万特用L5178Y小鼠淋巴瘤细胞进行体外微核试验时，对胞嘧啶阿拉伯糖苷，长春碱，5-氟尿嘧啶和2-氨基蒽进行了测试，具有不同的细胞毒性测量结果，以支持经合组织体外哺乳动物细胞微核试验的试验指南草案。
2. Etoposide, cadmium chloride, benzo(a)pyrene, cyclophosphamide and colchicine tested in the in vitro mammalian cell micronucleus test (MNvit) in the presence and absence of cytokinesis block using L5178Y mouse lymphoma cells and 2-aminoanthracene tested in MNvit in the absence of cytokinesis block using TK6 cells at AstraZeneca UK, in support of OECD draft Test Guideline 487. [J] . Fellows MD, ODonovan MR Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2010,第2期

机译：在存在和不存在胞质分裂阻滞的情况下，在体外哺乳动物细胞微核试验（MNvit）中使用依托泊苷，氯化镉，苯并（a）re，环磷酰胺和秋水仙碱，使用L5178Y小鼠淋巴瘤细胞进行胞质分裂阻滞，在不使用MNvit的情况下在MNvit中测试2-氨基蒽在英国阿斯利康使用TK6细胞进行胞质分裂阻滞，以支持OECD测试准则草案487。
3. Vinblastine and diethylstilboestrol tested in the in vitro mammalian cell micronucleus test (MNvit) at Swansea University UK in support of OECD draft Test Guideline 487. [J] . Johnson GE, Jenkins GJ, Thomas AD, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2010,第2期

机译：在英国斯旺西大学的体外哺乳动物细胞微核试验（MNvit）中对长春碱和二乙基雌二醇进行了试验，以支持OECD测试指南487。
4. MICRONUCLEUS TEST IN PERIPHERAL ERYTHROCYTES OF FISH: VARIABILITY IN MICROSCOPE SCORING [C] . Daniela Conti, Sabrina Barbizzi, Vanessa Bellaria, International Workshop on Combining and Reporting Analytical Results . 2007

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5. Utility of a genetic test in Saccharomyces cerevisiae and an immunofluorescence micronucleus test in Chinese hamster cells for the detection of antianeuploidogens [D] . Verma, Anuradha 1993

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6. A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride [O] . Kyung-Taek Rim, Soo-Jin Kim 2015

机译：工作中化学品危险性分类的致突变性测试综述-专注于氯丙烯的体内微核测试
7. Test No. 474: Mammalian Erythrocyte Micronucleus Test [O] . 2016

机译：测试No.474：哺乳动物红细胞微核试验
8. Results of an Oral Prenatal Developmental Toxicity Study in Rats, an Oral Reproduction/Developmental Toxicity Screening Test in Rats, a 13-Week Oral Toxicity Study in Rats, an In vivo Mammalian Erythrocyte Micronucleus Test in Mice, an In Vivo Micronucleu [R] . 2011

机译：大鼠口服产前发育毒性研究结果，大鼠口服繁殖/发育毒性筛查试验，大鼠13周口服毒性研究，小鼠体内哺乳动物红细胞微核试验，体内微核

Results of a Micronucleus Screening Test In Vivo Performed on the Basis of OECD 474 Mammalian Erythrocyte Micronucleus Test with Test Substance LS 5869752.

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