DRYING OF CEFPODOXIME PROXETIL USING SATURATED LIQUID CARBON DIOXIDE

摘要

A method for drying cefpodoxime proxetil is provided to obtain the cefpodoxime proxetil with almost no remaining solvent with reduced cost and drying time by performing a drying process using a saturated liquid CO2, which is relatively cheap, harmless to human body and non-reactive with a product. A method for drying cefpodoxime proxetil comprises a step of removing at least one remaining organic solvent selected from the group consisting of diisopropylether, ethyl acetate and dichloromethane by circulating saturated liquid carbon dioxide using a reboiler and a condenser without using a power unit such as a pump during a process of preparing the cefpodoxime proxetil.