TEST SYSTEM FOR ESTIMATING COMPATIBILITY OF BIOLOGICALLY ACTIVE SUBSTANCES WITH POLYMERS

摘要

FIELD: biochemical methods.;SUBSTANCE: invention relates to test solvent, test system, and a method for estimating compatibility of biologically active substances with N-vinylpyrrolidone copolymers. Solubility of the latter are simulated by means of liquid mixture of 1,3-bis(pyrro;lidon-1yl)butane with certain compounds characterized by structural similarity with monomer units present in copolymer.;EFFECT: simplified prediction procedure.;6 cl, 5 ex