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Extraction of an Astragalus extract for the treatment of Hepatitis C
Extraction of an Astragalus extract for the treatment of Hepatitis C
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机译:黄芪提取物的提取物用于治疗丙型肝炎
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摘要
A herb Astragalus extract, or an active fraction thereof is suitable for use in the treatment of Hepatitis C. The extract or active fraction thereof may form part of a medicament or a food or dietary additive. The extract is preferably purified by a factor of ten with respect to the dried raw material and preferably it comprises at least one marker selected from the group of: Astragaloside I, formononetin-7-o- b -d-glucoside and 3'-hydroxyl-formononetin-7-o- b -d-glucoside. The extract is preferably for administering in conjunction with interferon and/or Ribavirin. A method of producing an extract of Astragalus, with said extract comprising at least one marker selected from the group of Astragaloside I, formononetin-7-o- b -d-glucoside and 3'-hydroxyl-formononetin-7-o- b -d-glucoside, comprises at least one alcoholic extraction (preferably with ethanol), at least one ethanol-water precipitation step and a systematic solvent fractionation step with a plurality of solvents of different polarity.
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机译:草药黄芪提取物或其活性成分适合用于治疗丙型肝炎。该提取物或其活性成分可以形成药物或食品或饮食添加剂的一部分。提取物优选相对于干燥的原料纯化十倍,并且优选包含至少一种选自以下的标记:黄芪甲苷I,福莫那汀-7-o-b-d-葡萄糖苷和3'-羟基-formononetin-7-o- b -d-葡萄糖苷。提取物优选用于与干扰素和/或利巴韦林联合施用。一种生产黄芪提取物的方法,所述提取物包含至少一种选自黄芪甲苷I,formononetin-7-o-b-d-葡糖苷和3'-羟基-甲酮素-7-o-b-的标记。 d-葡糖苷包括至少一种醇提取(优选用乙醇),至少一个乙醇-水沉淀步骤和具有多种极性不同的溶剂的系统溶剂分馏步骤。
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