首页> 外国专利> DERIVATIVE HAVING PPAR(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR) AGONISTIC ACTIVITY

DERIVATIVE HAVING PPAR(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR) AGONISTIC ACTIVITY

机译:具有派生性的PPAR(过氧化物酶增殖物激活的受体)的神经活性

摘要

PPROBLEM TO BE SOLVED: To provide a compound useful as a PPAR agonist. PSOLUTION: The compound is represented by formula (I) (wherein, the ring Q is a monocyclic aryl group that may be substituted or the like; YSP1/SPis a single bond, -NRSP6/SP- or the like; the ring A is a nonaromatic heterocyclic diyl or the like; formulae: -YSP2/SPand ZSP1/SP-are each a group represented by formula (II) or the like; in formula (II), RSP7/SP, RSP8/SPand RSP9/SPare each a lower alkyl group or the like, n is an integer of 0 to 3, and ZSP1/SPis a single bond, O, S or NRSP9/SP; the ring B is an aromatic carbocyclic diyl or the like; YSP3/SPis a lower alkenylene group or the like; and ZSP2/SPis COORSP3/SPor the like). PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:提供一种可用作PPAR激动剂的化合物。

解决方案:该化合物由式(I)表示(其中,环Q为可被取代的单环芳基等; Y 1 为单键,-NR < SP> 6 -等;环A为非芳香族杂环二基等;式:-Y 2 和Z 1 -均为a由式(II)等表示的基团;在式(II)中,R 7 ,R 8 和R 9 分别较低烷基等,n为0至3的整数,Z 1 为单键,O,S或NR 9 ;环B为芳香族碳环二基等; Y 3 是低级亚烯基等; Z 2 是COOR 3 等。

版权:(C)2009,日本特许厅&INPIT

著录项

  • 公开/公告号JP2009215300A

    专利类型

  • 公开/公告日2009-09-24

    原文格式PDF

  • 申请/专利号JP20090100563

  • 申请日2009-04-17

  • 分类号C07D211/34;A61P43;A61P3/06;A61P3/10;A61P3/04;A61P9/10;A61P9/12;A61P37;A61P1/04;A61P19/02;A61P1/18;A61P25;A61P17/06;A61P17;A61P19/10;A61P15;A61P35;A61P25/28;A61P25/16;C07D277/82;A61K31/496;C07D417/04;A61K31/551;C07D417/14;C07D241/44;A61K31/498;C07D215/38;C07D277/20;C07D277/42;C07D403/04;C07D401/04;C07D241/04;A61K31/495;A61K31/445;A61K31/5377;C07D513/04;C07D413/04;C07D405/14;A61K31/506;C07D487/08;A61K31/55;C07D405/04;C07D409/04;A61P29;A61K31/428;

  • 国家 JP

  • 入库时间 2022-08-21 19:45:03

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