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EFFECT PREDICTION METHOD FOR INTERFERON THERAPY AND PREDICTION KIT OF INTERFERON THERAPY

机译:干扰素治疗的效果预测方法及干扰素治疗的预测试剂盒

摘要

PROBLEM TO BE SOLVED: To provide a technique capable of predicting an effect of interferon therapy to hepatitis C virus (HCV) persistently-infected person.;SOLUTION: A subject is anticipated whether the subject will show excellent response (sustained virological response: SVR) or will show relapse of HCV by making concentration of a substance in a body fluid acquired from the subject being a HCV persistently-infected person specific a marker. As an instance of a body fluid, blood is usually pointed out. The marker substance is captured on a carrier such as a substrate on which an ion exchanger or metal chelator has been immobilized. The concentration of the marker substance can be measured by a mass spectrometry. A kit capable of easily performing this method is also provided.;COPYRIGHT: (C)2009,JPO&INPIT
机译:解决的问题:提供一种能够预测干扰素对丙型肝炎病毒(HCV)持续感染者的治疗效果的技术。解决方案:预期受试者是否会表现出优异的应答(持续病毒应答:SVR)或通过使从作为HCV持续感染者的受试者获取的体液中的某种物质的浓度成为特定标记来显示HCV的复发。作为体液的一个实例,通常会指出血液。标记物质被捕获在诸如离子交换剂或金属螯合剂已被固定在其上的载体例如基底上。标记物质的浓度可以通过质谱测定。还提供了一种可以轻松执行此方法的工具包。;版权所有:(C)2009,JPO&INPIT

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