METHOD FOR PREDICTION OF EFFECT OF INTERFERON THERAPY AND KIT FOR PREDICTION

摘要

It is intended to provide a technique capable of predicting an effect of interferon therapy for a patient with persistent hepatitis C virus infection. By using a concentration of a specific marker substance in a body fluid collected from a test subject, a patient with persistent hepatitis C virus infection as an index, it is predicted whether the test subject shows SVR by interferon therapy or has relapse of HCV after completion of interferon therapy. Examples of the body fluid include blood. The concentration of the marker substance can be measured by capturing the marker substance on a carrier such as a substrate on which an ion exchanger or a metal chelator has been immobilized, followed by performing mass spectrometry. A kit capable of easily performing the method is also provided.