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Effect prediction method and prediction kit for interferon therapy

机译:干扰素治疗的效果预测方法和预测试剂盒

摘要

PPROBLEM TO BE SOLVED: To provide a technique capable of predicting an effect of interferon therapy to hepatitis C virus (HCV) persistently-infected person. PSOLUTION: A subject is anticipated whether the subject will show excellent response (sustained virological response: SVR) or will show relapse of HCV by making concentration of a substance in a body fluid acquired from the subject being a HCV persistently-infected person specific a marker. As an instance of a body fluid, blood is usually pointed out. The marker substance is captured on a carrier such as a substrate on which an ion exchanger or metal chelator has been immobilized. The concentration of the marker substance can be measured by a mass spectrometry. A kit capable of easily performing this method is also provided. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:提供一种能够预测干扰素对丙型肝炎病毒(HCV)持续感染者的治疗效果的技术。

解决方案:通过使从受试者体内获得的物质浓缩成为HCV持续感染者,可以预测该受试者是否表现出出色的反应(持续的病毒学应答:SVR)或显示HCV复发。具体标记。作为体液的一个例子,通常会指出血液。标记物质被捕获在载体上,例如固定有离子交换剂或金属螯合剂的基质上。标记物质的浓度可以通过质谱测定。还提供了一种能够轻松执行此方法的套件。

版权:(C)2009,日本特许厅&INPIT

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