METHOD FOR MAINTAINING PROLIFERATION POTENCY-DIFFERENTIATION POTENCY OF MESENCHYMAL STEM CELL

摘要

PPROBLEM TO BE SOLVED: To provide a method for maintaining the proliferation potency-differentiation potency of a mesenchymal stem cell, especially the stem cell derived from the human adult bone marrow. PSOLUTION: The method for maintaining the proliferation potency-differentiation potency of the mesenchymal stem cell, especially the stem cell derived from the human adult bone marrow includes introducing a transcription factor Sox2 or a Nanog gene derived from a mammal to the mesenchymal stem cell by using a (retrovirus) vector to induce the gene expression compulsorily-stably, or carrying out the introduction of the Sox2 gene in combination with the addition of bFGF of a growth factor to a medium. PCOPYRIGHT: (C)2009,JPO&INPIT