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MEDICINE COMPRISING COMBINATION OF PPAR ALPHA/GAMMA DUAL AGONIST AND DIABETES TREATING AGENT

机译:包含PPARα/γ双重激动剂和糖尿病治疗剂的药物

摘要

PROBLEM TO BE SOLVED: To provide a new medicine comprising a combination of PPAR α/γ dual agonist and a diabetes treating agent based on the finding that a medicinal agent having an excellent effect compared with the single administration of PPAR α/γ dual agonist is produced by the combination of the agonist and a diabetes treating agent.;SOLUTION: The administration of a medicine composed of a combination of PPAR α/γ dual agonist and a dipeptidyl peptidase IV inhibitor acting as a diabetes treating agent can keep the plasma glucose concentration after sugar tolerance test at a low level and decrease the necessary amount of insulin after sugar tolerance test.;COPYRIGHT: (C)2009,JPO&INPIT
机译:要解决的问题:提供一种包含PPARα/γ组合的新药。基于发现与单次施用PPARα/γ相比具有优异疗效的药物,发现双激动剂和糖尿病治疗剂。双重激动剂是通过激动剂和糖尿病治疗剂的组合产生的。解决方案:施用由PPARα/γ的组合组成的药物;双重激动剂和二肽基肽酶IV抑制剂作为糖尿病的治疗剂,可使糖耐量试验后的血浆葡萄糖浓度保持在较低水平,并减少糖耐量试验后的必要胰岛素量。;版权所有:(C)2009,JPO&INPIT

著录项

  • 公开/公告号JP2008285452A

    专利类型

  • 公开/公告日2008-11-27

    原文格式PDF

  • 申请/专利权人 ONO PHARMACEUT CO LTD;

    申请/专利号JP20070133874

  • 申请日2007-05-21

  • 分类号A61K45/06;A61K31/421;A61P3/10;

  • 国家 JP

  • 入库时间 2022-08-21 19:42:23

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