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Control of CCI-779 formulation stability by controlling drug substance impurities
Control of CCI-779 formulation stability by controlling drug substance impurities
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机译:通过控制原料药杂质来控制CCI-779制剂的稳定性
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摘要
A method of preparing a rapamycin composition having increased potency is provided. The method involves selecting a rapamycin compound having less than 1.5% oxidative and hydrolytic rapamycin impurities and formulating the selected rapamycin with an antioxidant and optional excipients.
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