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CONTROL OF CCI-779 DOSAGE FORM STABILITY THROUGH CONTROL OF DRUG SUBSTANCE IMPURITIES
CONTROL OF CCI-779 DOSAGE FORM STABILITY THROUGH CONTROL OF DRUG SUBSTANCE IMPURITIES
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机译:通过药物杂质的控制来控制CCI-779剂型的稳定性
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摘要
A method of preparing a rapamycin composition having increased potency is provided. The method involves selecting a rapamycin compound having less than 1.5% oxidative and hydrolytic rapamycin impurities and formulating the selected rapamycin with an antioxidant and optional excipients.
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