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INHIBITING THE SIGNS OF AGING BY INHIBITING NF-KAPPA B ACTIVATION
INHIBITING THE SIGNS OF AGING BY INHIBITING NF-KAPPA B ACTIVATION
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机译:通过抑制NF-κB激活来抑制衰老的迹象
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摘要
The present invention relates to methods and compositions for reducing and/or delaying one or more signs of aging which comprise inhibiting NF-kappa B activation. It is based, at least in part, on the discovery that a peptide which inhibits IKK-β interaction with NEMO, linked to a transducing peptide, inhibits the development of various indicia of senescence in a murine model of aging, Ercc1−/Δ mice.
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