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MAGE-C2 antigenic peptides and uses thereof

机译:MAGE-C2抗原肽及其用途

摘要

This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, β2 microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.
机译:本发明涉及衍生自MAGE-C2的分离的肽,编码MAGE-C2的核酸分子和衍生自MAGE-C2的分离的肽,包含该核酸分子的表达载体,用该核酸分子或DNA转化或转染的宿主细胞。表达载体,以及包含肽,HLA分子,β 2 微球蛋白以及第一和第二结合伴侣的四聚体。本发明还涉及使用本发明的肽,核酸分子,表达载体,四聚体和复合物的方法,以及与HLA分子复合识别该肽的溶细胞性T细胞。

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