Therapeutic fibrin-derived peptides and uses thereof

摘要

The invention relates to peptides having the general formula (I), or a salt or amide thereof, wherein R₁ and R₂ are either the same or different, wherein R₁ and R₂ are each selected from the group consisting of hydrogen and a saturated or unsaturated hydrocarbon residue, said residue having from 1 to 10 carbon atoms, wherein Z₁ is selected from the group consisting of histidine and proline, wherein Z₂ is selected from the group consisting of an arginine and a peptide comprising an initial arginine and having from 2 to 30 amino acids. The invention also relates to methods using the peptides of the present invention in the treatment of inflammation.