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Novel Tachykinin Peptides, Precursor Peptides Thereof And Genes Encoding The Same
Novel Tachykinin Peptides, Precursor Peptides Thereof And Genes Encoding The Same
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机译:新型速激肽,其前体肽及其编码基因
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摘要
Tachykinin peptide isolated and purified from the posterior salivary gland Octopus vulgaris which is mollusc. The tachykinin peptide provides a new approach for developing medicaments and pesticides through studies on the structural activity correlation at the molecular level, is characterized by:;(1) number of an amino acid resides is 12;;(2) N terminal of the peptide is Lys;;(3) an amino acid sequence of 5 amino acids from C terminal is represented by the following amino acid sequence (I),; —Phe-Xaa-Gly-Leu-Met-NH2 (I),;(wherein, Xaa is Val, Ile, Phe or Tyr), especially following amino acid sequence (1) and (2) are provided:; H-Lys-Pro-Pro-Ser-Ser-Ser-Glu-Phe-Val-Gly-Leu-Met-NH2 (1); H-Lys-Pro-Pro-Ser-Ser-Ser-Glu-Phe-Ile-Gly-Leu-Met-NH2 (2)
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机译:从后唾液腺寻常八达通 I>分离并纯化的速激肽。速激肽通过在分子水平上研究结构活性相关性,为药物和农药的开发提供了一种新方法,其特点是:(1)氨基酸残基数为12 ;;(2)该肽的N末端(3)从C末端起5个氨基酸的氨基酸序列由以下氨基酸序列(I)表示; <?in-line-formulae description =“在线表达式” end =“ lead”?>-Phe-Xaa-Gly-Leu-Met-NH 2 Sub>(I),<?in- (其中Xaa是Val,Ile,Phe或Tyr),特别是以下氨基酸序列(1)和(2): <?in-line-formulae description =“在线表达式” end =“ lead”?> H-Lys-Pro-Pro-Ser-Ser-Ser-Ger-Phe-Val-Gly-Leu-Met-NH < Sub> 2 Sub>(1)<?in-line-formulae description =“ In-line Formulae” end =“ tail”?>; <?in-line-formulae description =“在线表达式” end =“ lead”?> H-Lys-Pro-Pro-Ser-Ser-Ser-Ger-Phe-Ile-Gly-Leu-Met-NH < Sub> 2 Sub>(2)<?in-line-formulae description =“在线表达式” end =“ tail”?>
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