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Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases
Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases
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机译:压实的核酸纳米颗粒在非病毒性眼病治疗中的用途
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摘要
The present invention is a method of using compacted nucleic acid (such as DNA) nanoparticles for non-viral gene transfer to various tissues of the human eye or eyes of other mammals. These nanoparticles comprise, in one embodiment, a neutrally-charged complex containing a single molecule of plasmid DNA compacted with polyethylene glycol (PEG)-substituted poly lysine peptides.
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