modified-release oral medicinal product of at least one active ingredient in multi-capsule form

摘要

ORAL MEDICINAL PRODUCT FOR A MODIFIED RELEASE AT LEAST ONE ACTIVE PRINCIPLE IN MULTIMICROCAPSULAR FORM. The field of the invention is that of oral medicaments or pharmaceutical compositions, more particularly those of one or more active ingredients. The purpose of the invention is to provide an improved oral medicament that can be administered in one or more daily intakes, modified-release active ingredient (in particular an active ingredient), allowing to improve the prophylactic and therapeutic efficacy of that medicament. This purpose is achieved by the multi-capsular oral galenic form according to the invention, in which PA release is governed by a dual release triggering mechanism: "triggering time" and "triggering pH". This medicament comprises modified-release active ingredient microcapsules, each comprising a core comprising the active ingredient and one or more swelling agents and at least one coating which enables the modified release of the active ingredient.