STRUCTURE ENCLOSING HEMATOPOIETIC PROGENITOR CELLS FROM ES CELLS AND METHOD FOR PREPARING BLOOD CELLS USING THE SAME

摘要

It is intended to provide a net-like structure enclosing hematopoietic progenitor cells, a method for preparing the net-like structure, and a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the net-like structure. The invention provides a net-like structure enclosing hematopoietic progenitor cells obtained by plating ES cells on feeder cells and culturing the cells under conditions suitable for induction of differentiation of the hematopoietic progenitor cells. Further, it provides a method for producing various blood cells by further culturing hematopoietic progenitor cells enclosed in the net-like structure under conditions suitable for induction of differentiation of blood cells.