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PROCESS FOR PREPARING 2-BUTANOL BY ENZYMATIC REDUCTION OF 2-BUTANONE IN A TWO-PHASE SYSTEM
PROCESS FOR PREPARING 2-BUTANOL BY ENZYMATIC REDUCTION OF 2-BUTANONE IN A TWO-PHASE SYSTEM
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机译:两相体系中2-丁酮的酶还原制备2-丁醇的方法
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摘要
The invention relates to a process for the preparation of 2-butanol by enzymatic-catalyzed reduction of 2-butanone with a carbonyl reductase and a coenzyme and is characterized in that an aqueous phase, which contains the carbonyl reductase and the coenzyme, is contacted with an alcoholic phase, which is not miscible with the aqueous phase and contains 2-butanone, in order to reduce the 2-butanone, with the proviso that the alcohol present in the alcoholic phase is a secondary alcohol capable of regenerating the coenzyme and exhibiting a boiling point which lies above that of water, whereupon the 2-butanol formed is separated.
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