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DIARYL HARVEST DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS

机译：日记收获衍生物及其作为氯离子通道阻滞剂的用途

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摘要

The present invention relates to novel diarylurea derivatives useful as chloride channel blockers. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of bone metabolic diseases, diseases responsive to modulation of the mast cell or basophil activity, diseases responsive to inhibition of angiogenesis, or sickle cell anaemia, and to pharmaceutical compositions comprising the compounds of the invention.

机译：本发明涉及用作氯通道阻滞剂的新型二芳基脲衍生物。在其他方面，本发明涉及这些化合物在治疗方法中的用途，例如用于治疗骨代谢疾病，对肥大细胞或嗜碱性粒细胞活性的调节有响应的疾病，对抑制血管生成有响应的疾病或镰状细胞。贫血，以及包含本发明化合物的药物组合物。

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公开/公告号AT435199T

专利类型
公开/公告日2009-07-15

原文格式PDF
申请/专利权人 NEUROSEARCH A/S;
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申请/专利号AT20030793605T
发明设计人 DAHL BJARNE;CHRISTOPHERSEN PALLE;ENGSIG MICHAEL;KARSDAL MORTEN;FOGED NIELS;JENSEN FLEMMING;
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申请日2003-09-04
分类号C07C275/26;C07D277/20;A61K31/17;A61K31/19;A61K31/192;A61K31/401;A61K31/41;A61K31/426;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/661;A61K31/69;A61P1/04;A61P1/12;A61P7/06;A61P9;A61P9/10;A61P9/12;A61P11/06;A61P13;A61P17;A61P17/06;A61P17/08;A61P17/10;A61P19;A61P27/02;A61P27/06;A61P29;A61P35;A61P35/04;A61P37/08;A61P43;C07C275/28;C07C275/30;C07C275/42;C07D207;C07D207/16;C07D209/40;C07D213/75;C07D213/81;C07D213/82;C07D231/40;C07D257/04;C07D277/48;C07D295/192;C07D307/68;C07D333/36;C07D401/12;C07F5/02;C07F9/38;C07F9/58;
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入库时间 2022-08-21 19:24:21

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