PROCESS FOR THE OXIDATIVE CLEAVAGE OF VINYLAROMATICS USING PEROXIDASES OR LACCASES

摘要

The invention relates to a process for the oxidative cleavage of vinylaromatics of the formula (1), characterized in that compounds of the formula (1) are oxidized in the presence of molecular oxygen using at least one enzyme selected from among peroxidases and laccases as catalysts according to the reaction scheme below to form aldehydes or ketones of the formulae (2) and (3); where n is an integer from 0 to 5; the radicals R1 are selected from among saturated or unsaturated hydrocarbon groups which have from 1 to 10 carbon atoms and in which carbon atoms may be replaced by heteroatoms and may be further substituted, amino, C1-6-alkylamino and C1-6-dialkylamino groups, halogens, hydroxy and cyano, where two of the substituents R1 may be joined to form a ring; R2 and R3 are each, independently of one another, hydrogen or one of the options for R1, where R2 and/or R3 may be joined to an R1 to form a ring and R2 or R3 may each be a chemical bond.