GAMBOGIC GLYCOSIDE DERIVATIVES AND ANALOGS, THE PREPARATION AND THE APPLICATION THEREOF

摘要

The invention discloses gambogic glycoside derivatives and analogs represented by formula I, the preparation and the application thereof, wherein the substituents R1-R12 are defined as in the description. The gambogic glycoside derivatives and analogs of the invention were synthesized from extracted and purified gambogic acid. The obtained gambogic glycoside derivatives and analogs have antitumor, antivirus, antibacterial and antifungal activities and can be used as antitumor, antivirus, immune, antibacterial and antifungal medicines. The gambogic glycoside derivatives and analogs of the invention can be used together with other known antitumor, antivirus, immune, antibacterial and antifungal medicines.