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USE OF BIOMARKERS OF ALZHEIMER'S DISEASE FOR DIAGNOSTIC TESTS AND DRUG SCREENING

机译:阿尔齐默氏病生物标志物在诊断和药物筛查中的应用

摘要

The invention relates to method of diagnosing Alzheimer's disease or detecting a predisposition to Alzheimer's disease including providing a test cell sample from a subject, exposing the test cell sample to labeled amyloid beta peptides, and determining the level of labeled amyloid beta peptides in the test cell sample, wherein lower levels of labeled amyloid beta peptides in the test cell sample compared to a control cell sample are indicative of Alzheimer's disease.
机译:本发明涉及诊断阿尔茨海默氏病或​​检测阿尔茨海默氏病易感性的方法,包括提供来自受试者的测试细胞样品,将测试细胞样品暴露于标记的淀粉样β肽,并确定测试细胞中标记的淀粉样β肽的水平。样品,其中与对照细胞样品相比,在测试细胞样品中较低水平的标记淀粉样蛋白β肽水平指示阿尔茨海默氏病。

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